Moreover, in this process, the selected protease, nature of proteins, and ambient hydrolysis conditions considerably affect the yield (Koirala et al., 2023)
Focusing on the structures of these enzymes, in particular their acyl-binding pockets, catalytic motifs and subcellular distribution, helps to clarify why they prefer L-lactyl donors and how they generate the diverse functional consequences of lactylation
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In severe cases, this can trigger hyponatremia, a dangerously low sodium level that produces cramps, headaches, confusion, and in extreme cases seizures
10.1371/journal.pone.0142438 130 NaitoY.UchiyamaK.HandaO.AoiW